
邱霓,廣州醫(yī)科大學(xué)附屬腫瘤醫(yī)院乳腺腫瘤外科,副教授,碩士生導(dǎo)師
廣州市高層次人才“青年后備人才”
University of Kansas Medical Center和 University of Tennessee Health Science Center 訪問學(xué)者
基本情況簡(jiǎn)介:
在廣州醫(yī)科大學(xué)附屬腫瘤醫(yī)院乳腺腫瘤外科工作十余年,擔(dān)任廣東省抗癌協(xié)會(huì)遺傳性腫瘤專業(yè)委員會(huì)委員、廣東省醫(yī)療行業(yè)協(xié)會(huì)乳腺??乒芾矸謺?huì)委員、廣州市醫(yī)學(xué)會(huì)乳腺分會(huì)委員、廣東省老年保健協(xié)會(huì)乳腺疾病專業(yè)委員會(huì)委員。主持國(guó)家自然科學(xué)基金1項(xiàng)、中國(guó)博士后面上資助項(xiàng)目1項(xiàng)、中國(guó)博士后特別資助項(xiàng)目1項(xiàng)、廣東省自然科學(xué)基金項(xiàng)目4項(xiàng)、廣東省教育廳項(xiàng)目1項(xiàng)、廣州市屬高??蒲许?xiàng)目、廣州市教育局項(xiàng)目等多項(xiàng)課題;以第一作者在Nature Communication、Cancer Letters, Theranostics等國(guó)際權(quán)威期刊發(fā)表SCI論文十余篇。
聯(lián)系方式: [email protected];
研究領(lǐng)域
1、 細(xì)胞外基質(zhì)調(diào)控乳腺癌侵襲轉(zhuǎn)移的機(jī)理
2、 細(xì)胞代謝與乳腺癌耐藥的機(jī)制研究
科研項(xiàng)目
1、 國(guó)家自然科學(xué)基金青年項(xiàng)目,多囊蛋白1調(diào)控谷氨酰胺代謝促三陰性乳腺癌侵襲轉(zhuǎn)移的機(jī)制研究,2021年-2023年,24萬
2、 廣東省自然科學(xué)基金,面上項(xiàng)目, DYNLT1加速線粒體裂變促三陰性乳腺癌侵襲轉(zhuǎn)移的機(jī)制研究, 2023- 2025, 10萬元
3、 廣州市科技局市校企聯(lián)合項(xiàng)目,機(jī)械敏感鈣離子通道TRPP2介導(dǎo)細(xì)胞外基質(zhì)力學(xué)信號(hào)調(diào)控乳腺癌侵襲轉(zhuǎn)移的機(jī)制研究,2025-2026,20萬
4、 廣東省自然科學(xué)基金面上項(xiàng)目, ANKS6-原纖毛-Integrin信號(hào)軸在乳腺癌細(xì)胞群體性遷移中的機(jī)制研究, 2020-2022, 10萬元
5、 廣東省教育廳特色創(chuàng)新項(xiàng)目, DYNLT1維持線粒體穩(wěn)定性介導(dǎo)乳腺癌化療耐藥的機(jī)制研究, 2020-2022, 5萬元
代表性論著(*第一作者,#通訊作者)
(1)Liyun Luo*; Zhijie Zhang*; Ni Qiu*; Li Ling; Xiaoting Jia; Ying Song; Hongsheng Li;Jiansheng Li; Hui Lyu; Hao Liu; Zhimin He; Bolin Liu; Guopei Zheng ; Disruption of FOXO3a-miRNA feedback inhibition of IGF2/IGF-1R/IRS1 signaling confers Herceptin resistance in HER2-positive breast cancer, Nature Communications, 2021, 12(1)
(2)Ni Qiu*; Xue-Mei Wei; Zhi-Jie Zhang; Yu-Lian He; Xin-Ke Zhou; Yan Xiong ; Asymmetrical dimethylarginine induces dysfunction of insulin signal transduction via endoplasmic reticulum stress in the liver of diabetic rats, Life Sciences, 2020, 260: 118373
(3) Zhijie Zhang*; Ni Qiu*; Jiang Yin*; Jianlei Zhang; Hao Liu; Wei Guo; Meijun Liu; Ting Liu; Danyang Chen; Kai Luo; Hongsheng Li; Zhimin He; Jinbao Liu; Guopei Zheng ; SRGN crosstalks with
YAP to maintain chemoresistance and stemness in breast cancer cells by modulating HDAC2 expression, Theranostics, 2020, 10(10): 4290-4307
(4) Ni Qiu*; Yu-fang He; Si-ming Zhang; Yongtao Zhan; Guodong Han; Ming Jiang; Weixing He; Jie Zhou; Hongling Liang; Xiang Ao; Haoming Xia; Jia Li; Yu-yang Yang; Zhimin He; Zheng-zhi Zou; Hongsheng Li ; Cullin7 enhances resistance to trastuzumab therapy in Her2 positive breast cancer via degrading IRS-1 and downregulating IGFBP-3 to activate the PI3K/AKT pathway, Cancer Letters,2019, 2019(464): 25-36