張林啟，廣州醫(yī)科大學(xué)附屬腫瘤醫(yī)院核醫(yī)學(xué)科，主治醫(yī)師，碩士生導(dǎo)師,美國埃默里大學(xué)訪問學(xué)者
基本情況簡介：
在廣州醫(yī)科大學(xué)附屬腫瘤醫(yī)院核醫(yī)學(xué)科工作十余年，擔(dān)任，廣州市醫(yī)師學(xué)會核醫(yī)學(xué)與分子影像分會副主任委員，廣東省醫(yī)學(xué)會核醫(yī)學(xué)分會青年委員。主持國家和省部級課題3項，發(fā)表論文30余篇。
聯(lián)系方式: 郵箱[email protected]；
研究領(lǐng)域
1、肝臟惡性腫瘤診療分子影像可視化研究
2、新型PET分子探針研發(fā)
科研項目
1. 國家自然科學(xué)基金委員會，青年項目，82101994，基于多頻率3D磁共振彈性成像技術(shù)早期預(yù)測肝細(xì)胞癌靶向治療響應(yīng)的定量可視化研究，2022-01至2024-12，30萬
2. 廣東省自然科學(xué)基金，面上項目，2024A1515011956, 基于多模態(tài)影像技術(shù)可視化腫瘤微環(huán)境變化早期預(yù)測肝癌免疫治療耐藥及逆轉(zhuǎn)策略，2024-1至2026-12，15萬
3. 廣州醫(yī)科大學(xué)附屬腫瘤醫(yī)院，臨床研究5555計劃基金；先進(jìn)項目；IIT-2022-015(HYX)；18F-FDG PET/CT及18F-FAPI PET/CT對惡性腫瘤診斷的前瞻性對比研究，2023年2月至2026年2月，15萬
4. 廣州醫(yī)科大學(xué)附屬腫瘤醫(yī)院，人才培養(yǎng)項目，飛鷹人才，基于谷氨酰胺代謝PET顯像早期預(yù)測肝細(xì)胞癌免疫治療響應(yīng)的定量可視化研究，2023年7月至2026年7月，8萬
5. 廣東省自然科學(xué)基金，面上項目，2019A1515010845，基于多模態(tài)影像技術(shù)探索宮頸癌放療后機(jī)能不全性骨折演變的機(jī)制研究，2019-10至2022-09，10萬
代表性論著（*第一作者，#通訊作者）
1. Jing Zhang#, Qiao He#, Shuqin Jiang#, Mengsi Li, Haibao Xue, Donghui Zhang, Shuyi Li, Hao Peng, , Jiuceng Liang, Zhidong Liu, Songquan Rao, Jin Wang, Rusen Zhang*, Linqi Zhang*.18F-FAPI PET/CT in the Evaluation of Focal Liver Lesions with Non18F-FDG Avidity.Eur J Nucl Med Mol Imaging, 2023, 50: 937–950 .(SCIE，IF: 8.6 )
2. Jiucen Liang#, Shuqin Jiang#, Jingjing Song#, Danyang Chen, Shaojuan Weng, Shuyi Li, Hao Peng, Zhidong Liu, Jing Zhang, Yuanlin Chen, Songquan Rao, Haipeng Chen, Rusen Zhang*, Hao Liu*, Linqi Zhang*. Role of [18F]FAPI-04 in staging and therapeutic management of intrahepatic cholangiocarcinoma: prospective comparison with [18F]FDG PET/CT. EJNMMI Res, 2024, 14(1):81. (SCIE，IF: 3.1)
3. Jiucen Liang#, Jing Zhang#, Jingjing Song, Rusen Zhang, Linqi Zhang*. Intense 18F-FAPI Uptake in Small Recurrent Lesions of Combined Hepatocellular-Cholangiocarcinoma Negative on 18F-FDG PET/CT. Clin Nucl Med, 2024,49(7):e351-e353. (SCIE，IF: 10)
4. Jing Zhang#, Shuqin Jiang#, Mingsi Li#, Haibao Xue, Xi Zhong, Shuyi Li, Hao Peng, Jiuceng Liang, Zhidong Liu, Songquan Rao, Haipeng Chen, Zewen Cao, Yuanfeng Gong, Guoshuo Chen, Rusen Zhang*, Linqi Zhang*. Head-to-head comparison of 18F-FAPI and 18F-FDG PET/CT in staging and therapeutic management of hepatocellular carcinoma.Cancer Imaging. 2023, 23(1):106. (SCIE，IF: 3.5)
5. Jing Zhang#, Shuqin Jiang#, Rusen Zhang, Linqi Zhang*. Increased 18F-FAPI Uptake in Radiation Induced Liver Injury.Clin Nucl Med, 2023;48: e474–e476. (SCIE，IF: 10)
6. Linqi Zhang#, Zhidong Liu#, Shuqin Jiang, Qiao He, Rusen Zhang*.68Ga-FAPI Versus 18F-FDG PET/CT in Recurrent Undifferentiated Pleomorphic Sarcoma of Colon Mesentery.Clin Nucl Med, 2022; 47: e651–e653. (SCIE，IF: 10).
7. Linqi Zhang#, Xi Long#, Mayidili Nijiati, Tianhui Zhang, Mengsi Li, Ying Deng, Sichi Kuang, Yuanqiang Xiao, Jie Zhu, Bingjun He, Jingbiao Chen, Phillip Rossman, Kevin J Glaser, Sudhakar K Venkatesh, Richard L Ehman, Jin Wang*. Tumor stiffness measured by 3D magnetic resonance elastography can help predict the aggressiveness of endometrial carcinoma: preliminary findings. Cancer Imaging, 2021, 21(1):50. (SCIE，IF: 3.5)
8. Linqi Zhang#, Sichi Kuang#, Jingbiao Chen, Yao Zhang, Binliang Zhao, Hao Peng, Yuanqiang Xiao, Kathryn Fowler, Jin Wang*, Claude B Sirlin. The Role of Preoperative Dynamic Contrast-enhanced 3.0-T MR Imaging in Predicting Early Recurrence in Patients With Early-Stage Hepatocellular Carcinomas After Curative Resection. Front Oncol, 2019; 9:1336. (SCIE，IF: 3.5)
9. Linqi Zhang#, Qiao He#, Tao Zhou, Rusen Zhang*. Incidental Detection of Ovarian Thecoma by 99mTc-MDP Whole-Body Bone Scan: Contribution of Hybrid SPECT/CT. Clin Nucl Med 2019; 44: e577–e578. (SCIE，IF: 10)
10. Linqi Zhang#, Qiao He#, Tao Zhou, Bin Zhang, Wei Li, Hao Peng, Xi Zhong, Liwu Ma, Rusen Zhang*. Accurate characterization of (99m) Tc-MDP uptake in extraosseous neoplasm mimicking bone metastasis on whole-body bone scan: contribution of SPECT/CT. BMC Med Imaging, 2019;19(1): 44. (SCIE，IF: 2.9)
11. Linqi Zhang#, Qiao He#, Ming Jiang, Bin Zhang, Xi Zhong, Rusen Zhang*. Diagnosis of Insufficiency Fracture After Radiotherapy in Patients With Cervical Cancer: Contribution of Technetium 99mTc -Labeled Methylene Diphosphonate Single-Photon Emission Computed Tomography/Computed Tomography. Int J Gynecol Cancer, 2018; 28(7): 1369-76. (SCIE，IF: 4.5)
12. Linqi Zhang, Xu Zhang, Rusen Zhang, Wei Fan*. The role of initial 18F-FDG PET/CT in the management of patients with suspected extramedullary plasmocytoma. Cancer Imaging, 2018; 18 (1):19. (SCIE，IF: 3.5)
13. Linqi Zhang#, Qiao He#, Wei Li, Rusen Zhang*. The value of (99m) Tc-methylene diphosphonate single photon emission computed tomography/computed tomography in diagnosis of fibrous dysplasia. BMC Med Imaging, 2017;17(1): 46. (SCIE，IF: 2.9)
14. Linqi Zhang, Xu Zhang, Rusen Zhang, Fan Wei*. 18F-FDG PET/CT Metabolic Activity in a Patient With Solitary Extramedullary Plasmacytoma of the Lung. Clin Nucl Med, 2016; 41(3): 232-234. (SCIE，IF: 10)
15. Xi Zhong#, Linqi Zhang#, Tianfa Dong#, Hui Mai, Bingui Lu, Lu Huang and Jiansheng Li1*.Clinical and MRI features of sacral insufciency fractures after radiotherapy in patients with cervical cancer. BMC Womens Health 2022. 22:166. (SCIE，IF: 2.742)
16. Hao Peng#, Linqi Zhang#, Tao Zhou, Wen Li, Wei Li, Liwu Ma, Rusen Zhang*. Characterization of Solitary Lesions in the Extremities on Whole-Body Bone Scan in Patients With Known Cancer: Contribution of Single-Photon Emission Computed Tomography/Computed Tomography. Front Oncol, 2019, 9: 607. (SCIE，IF: 3.5)
17. Qiao He#, Linqi Zhang#, Bing Zhang , Xiangsong Zhang*. Use of 18F-FDG PET/CT for the Evaluation of Carcinoma Arising From Choledochal Cysts. Clin Nucl Med, 2019; 44(1): e51-e53. (SCIE，IF: 10)
18. Qiao He#, Linqi Zhang#, Bing Zhang, Xinchong Shi, Chang Yi, Xiangsong Zhang*. Diagnostic accuracy of 13N-ammonia PET, 11C-methionine PET and 18Ffluorodeoxyglucose PET: a comparative study in patients with suspected cerebral glioma. BMC Cancer, 2019; 19: 332. (SCIE，IF: 3.4)
19. Qiao He# , Bing Zhang#, Linqi Zhang*, Zhifeng Chen , Xinchong Shi , Chang Yi , Xiaoyan Wang , Xiangsong Zhang*. Diagnostic efficiency of 68Ga-DOTANOC PET/CT in patients with suspected tumour-induced osteomalacia. Eur Radiol, 2021; 31:2414-2421. (SCIE，IF: 4.7)
20. Qiao He#, Zhengkun Zhang#, Linqi Zhang#, Bing Zhang, Yali Long, Yuying Zhang, Zhihong Liao, Zhihao Zha*, Xiangsong Zhang*. Head-to-head comparison between [68Ga]Ga-DOTA-NOC and [18F]DOPA PET/CT in a diverse cohort of patients with pheochromocytomas and paragangliomas. Eur J Nucl Med Mol Imaging. 2024. 51:1989–2001. (SCIE，IF: 8.6）
